HTTP response header injection vulnerabilities arise when user-supplied data is copied into a response header in an unsafe way. If an attacker can inject newline characters into the header, then they can inject new HTTP headers and also, by injecting an empty line, break out of the headers into the message body and write arbitrary content into the application's response.
If possible, applications should avoid copying user-controllable data into HTTP response headers. If this is unavoidable, then the data should be strictly validated to prevent response header injection attacks. In most situations, it will be appropriate to allow only short alphanumeric strings to be copied into headers, and any other input should be rejected. At a minimum, input containing any characters with ASCII codes less than 0x20 should be rejected.